Structure of PDB 6fms Chain B Binding Site BS02

Receptor Information

>6fms Chain B (length=157) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PDVDRFGRLPWLWITVLVFVLDQVSKAFFQAELSMYQQIVVIPDLFSWTL
AYNTGAAFSFLADSSGWQRWLFALIAIVVSASLVVWLKRLKKGETWLAIA
LALVLGGALGNLYDRMVLGHVVDFILVHWQNRWYFPAFNLADSAITVGAV
MLALDMF

Ligand information

>6fms Chain G (length=4) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

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Receptor-Ligand Complex Structure

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Structure summary

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PDB	6fms In situ serial crystallography for rapid de novo membrane protein structure determination.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	F73 R116
Binding residue (residue number reindexed from 1)	F72 R115

Enzymatic activity

Enzyme Commision number

3.4.23.36: signal peptidase II.

Gene Ontology

	Molecular Function
GO:0004190	aspartic-type endopeptidase activity

	Biological Process
GO:0006465	signal peptide processing
GO:0006508	proteolysis

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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External links

PDB	RCSB:6fms, PDBe:6fms, PDBj:6fms
PDBsum	6fms
PubMed	30272004
UniProt	Q9HVM5\|LSPA_PSEAE Lipoprotein signal peptidase (Gene Name=lspA)

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