Structure of PDB 6f3h Chain B Binding Site BS02

Receptor Information
>6f3h Chain B (length=790) Species: 5478 (Nakaseomyces glabratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRGNMEQYQKAQKLSFDPAELLRTSLNVGDIVLLKQCTSELTMCVNLPQS
TTDPRYTFAKKDGTLVYAMKNSVILRIPKDLPEEVNQLLKRESNLPVLTR
QLIVSFTLATFTKFAWTQLPIVLKKLELIHRYLQDSRGSKHVNFMSLVRI
IKNLNIKEATDAYVRKVIDESMSVVNKSIDPTTLLATYWGVREQQQNNLW
GSVYTNTALLSPTTVAVLPLKKAHLFYQEVITRLESNDYQEIKAFAKLVN
DKDYHSIAKRYDYIRTLLNDYAAGNIEENAVLTTIISKIFRHIDMYRDQD
VTRSLCGKLLVEISPQSNSSNFILGNWDLNIPKGISSVEQKLYDTAMPTI
VTDRYDFGDMPVFCIDSEDAHEINDGISIEELDGVRSRIHIHIADPAGLF
PESFDYTKSGISDDVLRVSLKRAFTTYLPDLVVPMLPKSFCNRADLGKHD
RKTETISFSFELVNKEDGGLHVDYDTFQVRLGIVSNFPKVTYDKVDSILN
GDDNSLPSKQKKQLELLHTLATKLLHKRIHDDNAVVFGDGFNKGLVSLSP
DCIPTFYDQSQTKSTLLVSEFMILTNKLCAAFFQENKIPGVYRCYNGLNL
GNQAKAQFELLKENIKLGKLPSLKDITKISSQLSSSFYSPFPLPHKMIGN
TAYLTVTSPMRRGPDLINHLQLHRFLKKLPLCFKQEYLDQYVWSFQARAD
ILKIFQRHSSTYWTLKHLEQSGTKTHDVIVTSVPQNGTVNCLFPEYSYAR
GTLKLDPAMKKIPRIGDTIRHCKVESIHPLDGILTLTHVN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6f3h Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6f3h Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Resolution2.703 Å
Binding residue
(original residue number in PDB)		D469 D478
Binding residue
(residue number reindexed from 1)		D366 D375
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008859 exoribonuclease II activity
GO:0046872 metal ion binding
Biological Process
GO:0000957 mitochondrial RNA catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0045025 mitochondrial degradosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f3h, PDBe:6f3h, PDBj:6f3h
PDBsum6f3h
PubMed29311576
UniProtQ6FJE0

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