Structure of PDB 6ezu Chain B Binding Site BS02

Receptor Information
>6ezu Chain B (length=324) Species: 6183 (Schistosoma mansoni) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPIHGVETPNDNELEERFSLCLDEWGVDIFEIDRLSNGHALTTVAYRIFQ
KRDLLKTFCIDPHVFVRYLLRVESTYHADVPYHNSMHAADVLQTAHFLLQ
AEALDDVFSDLEILAVLFAAAIHDVDHPGVTNQFLINTGHELALQYNDAS
VLENHHLYMAFKILTEKDCDIFANLGGKKRQTLRRMVIELVLATDMSKHM
SLLADLRTMVETNLDNYADRIQILQNMIHCADLSNPAKPLRLYRKWTGRL
IEEFFRQGDKERELSLEISPMCDRESVEVEKSQVSFIDFVCHPLWETWCD
LVHPCAQLILDTLEDNRDWYECHI
Ligand information
Ligand IDAMP
InChIInChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyUDMBCSSLTHHNCD-KQYNXXCUSA-N
SMILES
SoftwareSMILES
CACTVS 3.370Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(O)=O)[CH](O)[CH]3O
CACTVS 3.370Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.7.6c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
ACDLabs 12.01O=P(O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.7.6c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
FormulaC10 H14 N5 O7 P
NameADENOSINE MONOPHOSPHATE
ChEMBLCHEMBL752
DrugBankDB00131
ZINCZINC000003860156
PDB chain6ezu Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ezu The structure of Schistosoma mansoni Phosphodiesterase 4A in complex with cAMP
Resolution2.04 Å
Binding residue
(original residue number in PDB)		H417 D458 M530 D575 L576 N578 L593 Q626 F629
Binding residue
(residue number reindexed from 1)		H83 D124 M196 D232 L233 N235 L250 Q283 F286
Annotation score1
Gene Ontology
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UnboundLocalError		Python 3.6.8: /usr/bin/python3
Wed Dec 18 19:36:13 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()
   1435     title=pdb2title(pdbid)
   1436     if bs.startswith("BS"):
=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)
   1438     else:
   1439         if lig3:
pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '6ezu', asym_id = 'B', bs = 'BS02', title = 'The structure of Schistosoma mansoni Phosphodiesterase 4A in complex with cAMP'
 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='6ezu', asym_id='B', bs='BS02', title='The structure of Schistosoma mansoni Phosphodiesterase 4A in complex with cAMP')
   1295         display_ec(ec,csaOrig,csaRenu)
   1296     if go:
=> 1297         display_go(go,uniprot,pdbid,asym_id)
   1298     return pubmed,uniprot
   1299 
global display_go = <function display_go>, go = '0004114,0007165,0008081', uniprot = '', pdbid = '6ezu', asym_id = 'B'
 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004114,0007165,0008081', uniprot='', pdbid='6ezu', asym_id='B')
    480         '''.replace("$namespace_link",namespace_link
    481           ).replace("$namespace",namespace
=>  482           ).replace("$uniprot",u
    483         ))
    484         for l,(term,name) in enumerate(go2aspect[Aspect]):
u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>