Structure of PDB 6d8p Chain B Binding Site BS02

Receptor Information
>6d8p Chain B (length=752) Species: 349102 (Cereibacter sphaeroides ATCC 17025) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKLF
HLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRPF
TFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRVG
VFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQRGLLGRVSDDMVQL
FEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALDDQEAGYR
TGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQARNVRLAP
KVEYVFDRTGAKSAEYAWRGLSQFGPFDRPSFANRSPRILVVYPSSTQGK
VENFLSAFRDGMGSNYSGFSKGFVDLMGLTKVEFVMCPVEVSSADRNGAH
TKYNSAIEDKLAGAGEVHAGIVVLFEDHARLPDDRNPYIHTKSLLLTLGV
PTQQVRMPTVLLEPKSLQYTLQNFSIATYAKLNGTPWTVNHDKAINDELV
VGMGLAELSGSRTEKRQRFVGITTVFAGDGSYLLGNVSKECEYEGYSDAI
RESMTGILRELKKRNNWRPGDTVRVVFHAHRPLKRVDVASIVFECTREIG
SDQNIQMAFVTVSHDHPFVLIDRSERGLEAYKGSTARKGVFAPPRGAISR
VGRLTRLLAVNSPQLIKRANTPLPTPLLVSLHPDSTFKDVDYLAEQALKF
TSLSWRSTLPAATPVTIFYSERIAELLGRLKSIPNWSSANLNIKLKWSRW
FL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6d8p Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		P45 R52 H62 W63 R97 K157 K245 E246 T249 Y260 Y329 Y341 Y494 A531 E532 H605 R606 S638 H639 D640 Q689 L690
Binding residue
(residue number reindexed from 1)		P26 R33 H43 W44 R78 K138 K220 E221 T224 Y235 Y304 Y316 Y469 A506 E507 H580 R581 S613 H614 D615 Q664 L665
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0044355 clearance of foreign intracellular DNA

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Molecular Function
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Biological Process
External links
PDB RCSB:6d8p, PDBe:6d8p, PDBj:6d8p
PDBsum6d8p
PubMed29996105
UniProtA4WYU7|AGO_CERS5 Protein argonaute (Gene Name=ago)

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