Structure of PDB 6czy Chain B Binding Site BS02

Receptor Information
>6czy Chain B (length=361) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSII
QKAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTG
SWGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICAN
ETIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGP
SGVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLV
FEDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVP
FTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLV
AFMKDFQAKHA
Ligand information
Ligand IDPMP
InChIInChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKeyZMJGSOSNSPKHNH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1CN)C
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
FormulaC8 H13 N2 O5 P
Name4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE;
PYRIDOXAMINE-5'-PHOSPHATE
ChEMBLCHEMBL1235353
DrugBankDB02142
ZINCZINC000001532708
PDB chain6czy Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6czy Structural Analysis of Phosphoserine Aminotransferase (Isoform 1) FromArabidopsis thaliana- the Enzyme Involved in the Phosphorylated Pathway of Serine Biosynthesis.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		G144 A145 T146 W171 T221 D241 S243 Q264 K265
Binding residue
(residue number reindexed from 1)		G75 A76 T77 W102 T152 D172 S174 Q195 K196
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Biological Process
GO:0006564 L-serine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6czy, PDBe:6czy, PDBj:6czy
PDBsum6czy
PubMed30034403
UniProtQ96255|SERB1_ARATH Phosphoserine aminotransferase 1, chloroplastic (Gene Name=PSAT1)

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