Structure of PDB 6cnp Chain B Binding Site BS02

Receptor Information
>6cnp Chain B (length=58) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVD
LSSFDFRT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnp Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		R188 S189 P191 R195
Binding residue
(residue number reindexed from 1)		R36 S37 P39 R43
Binding affinityPDBbind-CN: Kd=0.7uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6cnp, PDBe:6cnp, PDBj:6cnp
PDBsum6cnp
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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