Structure of PDB 5zyu Chain B Binding Site BS02
Receptor Information
>5zyu Chain B (length=223) Species:
9606
(Homo sapiens) [
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NWFPIFNPERSDKVPLKIPLQRNVIPSVTRVLQQTMTKQQVFLLERWKQR
MILELGEDGFKEYTSNVFLQGKRFHEALESILSPQNLLKSGYIESVQHIL
KDVSGVRALESAVQHETLNYIGLLDCVAEYQGKLCVIDWKTSEKPKPFIQ
STFDNPLQVVAYMGAMNHDTNYSFQVQCGLIVVAYKDGSPAHPHFMDAEL
CSQYWTKWLLRLEEYTEKKKNQN
Ligand information
>5zyu Chain C (length=8) [
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caacaaca
Receptor-Ligand Complex Structure
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PDB
5zyu
Structural insights into DNA degradation by human mitochondrial nuclease MGME1
Resolution
1.752 Å
Binding residue
(original residue number in PDB)
S132 T134 Q138 Q145 L149 W152 V172 F173 G176 K177 H180 G235 L236 D238 K253 T254 S255 E256 F266 Y275
Binding residue
(residue number reindexed from 1)
S27 T29 Q33 Q40 L44 W47 V67 F68 G71 K72 H75 G122 L123 D125 K140 T141 S142 E143 F153 Y162
Enzymatic activity
Enzyme Commision number
3.1.-.-
External links
PDB
RCSB:5zyu
,
PDBe:5zyu
,
PDBj:5zyu
PDBsum
5zyu
PubMed
30247721
UniProt
Q9BQP7
|MGME1_HUMAN Mitochondrial genome maintenance exonuclease 1 (Gene Name=MGME1)
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