Structure of PDB 5zw3 Chain B Binding Site BS02

Receptor Information
>5zw3 Chain B (length=193) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRYEQINDYIEALLKPRPDNVKRLEAYAEEHHVPIMEKAGMEVLLQILSV
KQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEFQ
LDDRIHVFYGDALELADAVHVTAPYDVIFIDAAKGQYQNFFHLYEPMLSP
DGVIITDNVLFIDEYNHWLMNHPDYQTAIIPVGDGLAISKKKR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5zw3 Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zw3 Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine.
Resolution2.27 Å
Binding residue
(original residue number in PDB)		D133 D159 N160
Binding residue
(residue number reindexed from 1)		D131 D157 N158
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0016300 tRNA (uridine) methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5zw3, PDBe:5zw3, PDBj:5zw3
PDBsum5zw3
PubMed29982645
UniProtO32036|TRMR_BACSU tRNA 5-hydroxyuridine methyltransferase (Gene Name=trmR)

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