Structure of PDB 5zln Chain B Binding Site BS02

Receptor Information

>5zln Chain B (length=753) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHH
LHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEE
LNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGN
CYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLV
SYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHP
ETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNMSVLDLSENFLYESIQHT
NAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFR
SLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRI
SGPSTLSKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLSLSHN
SIAQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNS
QPFSMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNSNSVRFLDFS
GNGMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLK
LLSLRDNYLSFFQWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKL
DVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLD
VRSNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDL
RLC

Ligand information

>5zln Chain D (length=10) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aggcgttttt

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5zln Structural basis for species-specific activation of mouse Toll-like receptor 9
Resolution	2.3 Å
Binding residue (original residue number in PDB)	W47 S72 R74 H77 W96 P99 S104 P105 L106 F108 Y180 Y208 Y229 N263
Binding residue (residue number reindexed from 1)	W20 S45 R47 H50 W69 P72 S77 P78 L79 F81 Y153 Y181 Y202 N236

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5zln, PDBe:5zln, PDBj:5zln
PDBsum	5zln
PubMed	29961984
UniProt	Q9EQU3\|TLR9_MOUSE Toll-like receptor 9 (Gene Name=Tlr9)

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