Structure of PDB 5zbr Chain B Binding Site BS02

Receptor Information
>5zbr Chain B (length=330) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKVKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPIGQPKIFAYDHCFW
SMDESVREKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTM
MGTADQPGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLD
PTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTESSRSHAVF
KITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERSNINKSLTTLGLVISAL
ADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDET
LSTLRYADRAKHIINHAVVNEDPNARIIRD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5zbr Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5zbr Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Y95 N96 N321 V358
Binding residue
(residue number reindexed from 1)		Y82 N83 N281 V318
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5zbr, PDBe:5zbr, PDBj:5zbr
PDBsum5zbr
PubMed29752968
UniProtA0A0G2K8Z9

[Back to BioLiP]