Structure of PDB 5ybp Chain B Binding Site BS02
Receptor Information
>5ybp Chain B (length=282) Species:
104259
(Penicillium brasilianum) [
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GLVPRGSHMPPRLQRFPATASADEIFAAFQEDGCVVIEGFEQVARFSQEV
DPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPFRNEIIESDLMHELCDRV
FSKPGEGMGYHFNDNMVIEVQPAPAQRLHRDQELYPWWNSMGPAGPECLI
NFFCAVTPFTEENGATRLVPGSHLWPEFTQINERDCPQFGKIETVPAMQP
GDCYLMSGKVIHGAGHNTTTDRRRALALSIIRRELRPMQAFSLSVPMKLA
REMSERSQTMFGFRSSFWGNDGKDIAHHLGLI
Ligand information
Ligand ID
AKG
InChI
InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6
C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385
OC(=O)CCC(=O)C(O)=O
Formula
C5 H6 O5
Name
2-OXOGLUTARIC ACID
ChEMBL
CHEMBL1686
DrugBank
DB08845
ZINC
ZINC000001532519
PDB chain
5ybp Chain B Residue 302 [
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Receptor-Ligand Complex Structure
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PDB
5ybp
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
Resolution
2.312 Å
Binding residue
(original residue number in PDB)
Q127 H130 F154 T167 H214 A216 R226
Binding residue
(residue number reindexed from 1)
Q126 H129 F153 T166 H212 A214 R223
Annotation score
5
Enzymatic activity
Enzyme Commision number
1.14.11.-
Gene Ontology
Molecular Function
GO:0046872
metal ion binding
GO:0051213
dioxygenase activity
Biological Process
GO:0016114
terpenoid biosynthetic process
GO:0140874
paraherquonin biosynthetic process
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:5ybp
,
PDBe:5ybp
,
PDBj:5ybp
PDBsum
5ybp
PubMed
29317628
UniProt
A0A1E1FFL0
|PRHA_PENBI Multifunctional dioxygenase prhA (Gene Name=prhA)
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