Structure of PDB 5wai Chain B Binding Site BS02

Receptor Information
>5wai Chain B (length=300) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIK
RKTFKVDDMLSKVEKMKGEQESAHLQLTFTGFFHKVTLEVLLVKVCHKKR
KDVSCPIRQVPTGKQVPLNPDLNQTKPSLAVSSNEFEPSNSHMVKSYSLL
FRFVAQMTVFDKNRRLQLLDGEYEVAMQEMQGPTLQFTLRWTGRQKLRIF
YQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYV
YHPKGARIDVSINECYDFSRNGPVKRTPITHILVCRPKRTKASMSEFLEW
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5wai Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wai Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C450 C453 H466 H471
Binding residue
(residue number reindexed from 1)		C221 C224 H237 H242
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5wai, PDBe:5wai, PDBj:5wai
PDBsum5wai
PubMed29499137
UniProtQ15022|SUZ12_HUMAN Polycomb protein SUZ12 (Gene Name=SUZ12)

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