Structure of PDB 5w7y Chain B Binding Site BS02
Receptor Information
>5w7y Chain B (length=103) Species:
9606
(Homo sapiens) [
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GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQL
RIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
IPS
Ligand information
>5w7y Chain C (length=8) Species:
9606
(Homo sapiens) [
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PYAGETDE
Receptor-Ligand Complex Structure
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PDB
5w7y
Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
R27 G28 P29 G32 I33 T34 K36 S39 R40 H58 N60
Binding residue
(residue number reindexed from 1)
R25 G26 P27 G30 I31 T32 K34 S37 R38 H56 N58
Enzymatic activity
Enzyme Commision number
3.1.-.-
Gene Ontology
Molecular Function
GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408
3'-5' exonuclease activity
Biological Process
GO:0006302
double-strand break repair
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Molecular Function
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Biological Process
External links
PDB
RCSB:5w7y
,
PDBe:5w7y
,
PDBj:5w7y
PDBsum
5w7y
PubMed
29059378
UniProt
Q8IW19
|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)
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