Structure of PDB 5ve9 Chain B Binding Site BS02

Receptor Information
>5ve9 Chain B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPGGHMANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFI
DGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAALHP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5ve9 Chain B Residue 7202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ve9 Structure of the ACF7 EF-Hand-GAR Module and Delineation of Microtubule Binding Determinants.
Resolution2.795 Å
Binding residue
(original residue number in PDB)		D7090 D7092 D7094 Y7096 E7101
Binding residue
(residue number reindexed from 1)		D73 D75 D77 Y79 E84
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0045104 intermediate filament cytoskeleton organization

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Molecular Function
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Biological Process
External links
PDB RCSB:5ve9, PDBe:5ve9, PDBj:5ve9
PDBsum5ve9
PubMed28602822
UniProtQ9UPN3|MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (Gene Name=MACF1)

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