Structure of PDB 5v1q Chain B Binding Site BS02

Receptor Information

>5v1q Chain B (length=440) Species: 1307 (Streptococcus suis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMRTISEDILFRLEKFGGILINKTNFERIELDETEAFFLYLVQNHGIEIA
TSFFKKEIEMGKLERALSLNIYSDNNIEDSLNNPYETLQNARKHVAKLKK
HNILSFPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKD
NGVLSVSILGGEPTRYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEIL
AKSKYITPVLSLQTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAV
YTKQSYEQIIELVDFCIENKIDRFSVANYSEVTGYTKIKKKYDLADLRRL
NEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEFDEMYYGCRA
KYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
RTKNSKCLSCGLLKICEGGCYVNLIKEKSPEYFRDSVCQL

Ligand information

InChI=1S/4Fe.4S

LJBDFODJNLIPKO-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.7	[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385	S1[Fe]S[Fe]1.S2[Fe]S[Fe]2

Formula

Fe4 S4

Name

IRON/SULFUR CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

5v1q Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5v1q Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	C406 C409 C415 G417 R433 C437
Binding residue (residue number reindexed from 1)	C407 C410 C416 G418 R434 C438
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:5v1q, PDBe:5v1q, PDBj:5v1q
PDBsum	5v1q
PubMed	28893989
UniProt	A0A0Z8EWX1

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