Structure of PDB 5un8 Chain B Binding Site BS02
Receptor Information
>5un8 Chain B (length=426) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKYSPQMALKLALTEWLQEFGVPHQYS
SVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVKIEEWRSRA
AKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWL
GCRSWAFRGGLAGEFQRLLPIDGAND
Ligand information
>5un8 Chain H (length=8) Species:
9606
(Homo sapiens) [
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WVDSTPPP
Receptor-Ligand Complex Structure
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PDB
5un8
Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Resolution
2.13 Å
Binding residue
(original residue number in PDB)
W645 K648 M653
Binding residue
(residue number reindexed from 1)
W384 K387 M392
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5un8
,
PDBe:5un8
,
PDBj:5un8
PDBsum
5un8
PubMed
28319083
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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