Structure of PDB 5t01 Chain B Binding Site BS02

Receptor Information

>5t01 Chain B (length=62) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMKAERKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELASTANML
REQVAQLKQKVM

Ligand information

>5t01 Chain D (length=19) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aatggacgagtcataggag

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	5t01 Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.
Resolution	1.89 Å
Binding residue (original residue number in PDB)	R259 N262 R263 R270
Binding residue (residue number reindexed from 1)	R8 N11 R12 R19
Binding affinity	PDBbind-CN: Kd=0.011uM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5t01, PDBe:5t01, PDBj:5t01
PDBsum	5t01
PubMed	28158710
UniProt	P05412\|JUN_HUMAN Transcription factor Jun (Gene Name=JUN)

[Back to BioLiP]