Structure of PDB 5sup Chain B Binding Site BS02

Receptor Information
>5sup Chain B (length=383) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLG
KTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK
TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN
FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRF
LQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVII
FVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV
STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS
SKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5sup Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		N138 A139 R140 Y166 G167 G168 T191 G193 R194 E223 K314 S315 H337 G338 R345 T363 V365
Binding residue
(residue number reindexed from 1)		N77 A78 R79 Y105 G106 G107 T130 G132 R133 E162 K253 S254 H276 G277 R284 T302 V304
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5sup, PDBe:5sup, PDBj:5sup
PDBsum5sup
PubMed28059701
UniProtQ07478|SUB2_YEAST ATP-dependent RNA helicase SUB2 (Gene Name=SUB2)

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