Structure of PDB 5nc7 Chain B Binding Site BS02
Receptor Information
>5nc7 Chain B (length=110) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
Ligand information
>5nc7 Chain X (length=7) Species:
1639
(Listeria monocytogenes) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
WPPPPTE
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5nc7
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
R34 Y38 R47 R51 N61 A63
Binding residue
(residue number reindexed from 1)
R33 Y37 R46 R50 N60 A62
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nc7
,
PDBe:5nc7
,
PDBj:5nc7
PDBsum
5nc7
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
[
Back to BioLiP
]
