Structure of PDB 5n9c Chain B Binding Site BS02
Receptor Information
>5n9c Chain B (length=110) Species:
9606
(Homo sapiens) [
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SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
Ligand information
>5n9c Chain H (length=3) Species:
32630
(synthetic construct) [
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PPt
Receptor-Ligand Complex Structure
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PDB
5n9c
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.16 Å
Binding residue
(original residue number in PDB)
E3 Y38 R47 R51 N61
Binding residue
(residue number reindexed from 1)
E2 Y37 R46 R50 N60
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5n9c
,
PDBe:5n9c
,
PDBj:5n9c
PDBsum
5n9c
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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