Structure of PDB 5lgy Chain B Binding Site BS02

Receptor Information
>5lgy Chain B (length=198) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPV
QLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQH
LIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCM
GGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRK
Ligand information
Receptor-Ligand Complex Structure
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PDB5lgy Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode.
Resolution2.92 Å
Binding residue
(original residue number in PDB)		S241 R273 C275 A276 R280
Binding residue
(residue number reindexed from 1)		S148 R180 C182 A183 R187
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lgy, PDBe:5lgy, PDBj:5lgy
PDBsum5lgy
PubMed27338200
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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