Structure of PDB 5kut Chain B Binding Site BS02

Receptor Information
>5kut Chain B (length=170) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKGQTQRSVLLCKVVGACGVGKSAFLQAFLGRGLGHQTREQPPGYAIDTV
QVNGQEKYLILCEVGTDGLLATSLDATCDVACLMFDGSDPKSFAHCASVY
KHHYMDGQTPCLFVSSKADLPEGVAVSGPSPAEFCRKHRLPAPVPFSCAG
PAEPSTTIFTQLATMAAFPH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5kut Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kut Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Resolution1.693 Å
Binding residue
(original residue number in PDB)		S430 E471
Binding residue
(residue number reindexed from 1)		S23 E63
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:5kut, PDBe:5kut, PDBj:5kut
PDBsum5kut
PubMed27605430
UniProtQ8IXI1|MIRO2_HUMAN Mitochondrial Rho GTPase 2 (Gene Name=RHOT2)

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