Structure of PDB 5jch Chain B Binding Site BS02

Receptor Information
>5jch Chain B (length=655) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKAS
EQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVV
KRYDVIICTAQILENSLLNESVRLSDFSLIIIDQCHHTQKEGVYNNIMRR
YLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKICANL
DACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQDIQK
YCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYNDALQI
NDTIRMVDAYNHLNNFYKELKRRKTAESDDSKQDETDEFLMRLFHAKKKQ
LKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHW
IMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLI
ATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYALVASSG
SGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIVEKQMK
AKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHKRENQT
NVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKKWGELP
IIFPD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5jch Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		N357 K358 V359 T406 Q408 K700 T701 R702 G730 S735 T763 T764 V765 K977
Binding residue
(residue number reindexed from 1)		N60 K61 V62 T109 Q111 K389 T390 R391 G419 S424 T452 T453 V454 K644
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5jch, PDBe:5jch, PDBj:5jch
PDBsum5jch
PubMed27203181
UniProtD9N195

[Back to BioLiP]