Structure of PDB 5iwa Chain B Binding Site BS02

Receptor Information
>5iwa Chain B (length=225) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEITVKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELE
RTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERGMPYVNQRWLGGMLT
NFKTISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFR
LLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPG
NDDAIRSIQLILSRAVDLIIQARGG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5iwa Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5iwa Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H19 D166 D191 D205
Binding residue
(residue number reindexed from 1)		H17 D163 D188 D202
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5iwa, PDBe:5iwa, PDBj:5iwa
PDBsum5iwa
PubMed27071098
UniProtP80371|RS2_THET8 Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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