Structure of PDB 5hjr Chain B Binding Site BS02

Receptor Information
>5hjr Chain B (length=83) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKP
LYILSSRVNDGVCDCCDGTDEYNSGTVCENTCR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5hjr Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5hjr Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
R91 D94 V96 D98 D104 E105
Binding residue
(residue number reindexed from 1)
R57 D60 V62 D64 D70 E71
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5hjr, PDBe:5hjr, PDBj:5hjr
PDBsum5hjr
PubMed27462106
UniProtO08795|GLU2B_MOUSE Glucosidase 2 subunit beta (Gene Name=Prkcsh)

[Back to BioLiP]