Structure of PDB 5ggi Chain B Binding Site BS02

Receptor Information
>5ggi Chain B (length=551) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAK
RVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSL
GSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPL
SSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPD
NKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMD
VVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDL
DIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETM
PGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVS
RSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVH
RLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKC
LHIWDLDVRGNHRGLWRLFRKKNHFLVVGVPASPYSVKKPPSVTPIFLEP
P
Ligand information
Receptor-Ligand Complex Structure
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PDB5ggi Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan
Resolution2.6 Å
Binding residue
(original residue number in PDB)		D474 M477 M481
Binding residue
(residue number reindexed from 1)		D378 M381 M385
Enzymatic activity
Catalytic site (original residue number in PDB) D395 D476
Catalytic site (residue number reindexed from 1) D299 D380
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0008375 acetylglucosaminyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5ggi, PDBe:5ggi, PDBj:5ggi
PDBsum5ggi
PubMed27493216
UniProtQ8WZA1|PMGT1_HUMAN Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (Gene Name=POMGNT1)

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