Structure of PDB 5fml Chain B Binding Site BS02

Receptor Information
>5fml Chain B (length=196) Species: 11520 (Influenza B virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAMDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVI
SDMNFLDEEGKSYTALEGQGKEQNLRPQYEVIEGMPRTIAWMVQRSLAQE
HGIETPKYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIF
SYNQDYSLSNESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5fml Chain B Residue 1195 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5fml Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H41 D109 E120 V121
Binding residue
(residue number reindexed from 1)		H43 D111 E122 V123
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:5fml, PDBe:5fml, PDBj:5fml
PDBsum5fml
PubMed26711008
UniProtQ5V8Z9

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