Structure of PDB 5f9k Chain B Binding Site BS02

Receptor Information
>5f9k Chain B (length=130) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMFKVKKLSDKAIIPQRGSKGAAGYDLSSAHELVVPAHGKALAMTDLQ
IAIPDGTYGRIAPRSGLAWKNFIDCGAGVIDSDYRGNVGVVLFNHSDVDF
KVAVGDRVAQLIFERIVTPEPLEVDEIDET
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5f9k Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5f9k Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus.
Resolution2.179 Å
Binding residue
(original residue number in PDB)		V79 D81
Binding residue
(residue number reindexed from 1)		V79 D81
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) A25 R64 G66 I73 D81
Catalytic site (residue number reindexed from 1) A25 R64 G66 I73 D81
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004170 dUTP diphosphatase activity
Biological Process
GO:0006226 dUMP biosynthetic process
GO:0046081 dUTP catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5f9k, PDBe:5f9k, PDBj:5f9k
PDBsum5f9k
PubMed31910901
UniProtQ54BW5|DUT_DICDI Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Gene Name=dut)

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