Structure of PDB 5f6c Chain B Binding Site BS02

Receptor Information
>5f6c Chain B (length=510) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRI
EPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQE
VIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRT
ELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAE
SRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGR
PDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEAL
TAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFID
MTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGES
SHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIAS
YLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLS
YMLPKLHEEA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5f6c Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5f6c Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Resolution3.002 Å
Binding residue
(original residue number in PDB)		D28 S393
Binding residue
(residue number reindexed from 1)		D29 S394
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5f6c, PDBe:5f6c, PDBj:5f6c
PDBsum5f6c
PubMed30270108
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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