Structure of PDB 5cd1 Chain B Binding Site BS02

Receptor Information
>5cd1 Chain B (length=321) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFE
VTSGGSLQPKTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMY
YAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMG
GFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSY
IQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVA
PSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHP
KLLMSGGGGYLLSGFTVAMDN
Ligand information
>5cd1 Chain N (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcccggauagcucagucgguagagcaucagacuuuuaaucugagggucc
aggguucaagucccuguucgggcgcc
.<<<<<<<..<<<<........>>>>.<<<<<.<...>.>>>>>.....<
<<<<.......>>>>>>>>>>>>...
Receptor-Ligand Complex Structure
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PDB5cd1 Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		V33 K150 K153 R175 E176 P177 K179 H182 V237 L444
Binding residue
(residue number reindexed from 1)		V16 K78 K81 R103 E104 P105 K107 H110 V165 L302
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0031515 tRNA (m1A) methyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5cd1, PDBe:5cd1, PDBj:5cd1
PDBsum5cd1
PubMed26470919
UniProtQ9UJA5|TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (Gene Name=TRMT6)

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