Structure of PDB 5boe Chain B Binding Site BS02

Receptor Information
>5boe Chain B (length=433) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVE
LRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALD
GTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMN
IVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGL
ETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEF
YENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWD
GWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTL
TETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSR
TDRIAKYNQLLRIEDELFETAKYDGIKSFYNLD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5boe Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5boe Octameric structure of Staphylococcus aureus enolase in complex with phosphoenolpyruvate
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D244 E291 D318
Binding residue
(residue number reindexed from 1)		D244 E291 D318
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) S42 H157 E166 E207 D244 E291 D318 K343 H371 K394
Catalytic site (residue number reindexed from 1) S42 H157 E166 E207 D244 E291 D318 K343 H371 K394
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0009986 cell surface

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5boe, PDBe:5boe, PDBj:5boe
PDBsum5boe
PubMed26627653
UniProtO69174|ENO_STAAU Enolase (Gene Name=eno)

[Back to BioLiP]