Structure of PDB 5a2z Chain B Binding Site BS02

Receptor Information
>5a2z Chain B (length=462) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTFTEVQTERLEQADRSVLIKCPSKLNEKKLLQYLSSHGKIDNYFFFENR
GIHALIEFSEKSSVASLQAVTGIPKHVVPYKSRLFTFTLKNPGSQAAEER
PVKISPQSHIPVNELIPKLCHADSISSQMYILLNEYQLTEENIKLRYLAC
SLVRDFARAYFPDSTVKPFGSSVNTFGKLGCDVDMFLDFHKGPFEMEYQM
KRLPSERLATQKILSIIGDCLDNFGPGYSSVQKILNARCPLVKFSHQPTG
FQCDLSVSNSIAIRCSELLYIYGCLDPRVRALVFSLRCWARVHGLTNSVP
GTWITNFSLTMMIMFFLQKRSPPIIPTLDQLKELADEKDKHVIGGYDCSF
VSDLSKIKPTKNTETLDELLCDFFQYFGNFDFRKNSLNLRKGKEVNKPES
SPLYIWNPFEQDLNISKNVNQPQLEKFVAMARESAWILQKEDKTQQMINK
EPWGLAAVLIPF
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5a2z Chain B Residue 1529 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5a2z Structure of Mitochondrial Poly(A) RNA Polymerase Reveals the Structural Basis for Dimerization, ATP Selectivity and the Spax4 Disease Phenotype.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		D237 D239
Binding residue
(residue number reindexed from 1)		D182 D184
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G283 G290 K298 I408 S465
Catalytic site (residue number reindexed from 1) G218 G225 K233 I343 S400
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0002134 UTP binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016740 transferase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:1990817 poly(A) RNA polymerase activity
Biological Process
GO:0000965 mitochondrial RNA 3'-end processing
GO:0016070 RNA metabolic process
GO:0071044 histone mRNA catabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5a2z, PDBe:5a2z, PDBj:5a2z
PDBsum5a2z
PubMed26319014
UniProtF1NBW0

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