Structure of PDB 4zq9 Chain B Binding Site BS02
Receptor Information
>4zq9 Chain B (length=189) Species:
648242
(Adeno-associated virus 2 Srivastava/1982) [
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PGFYEIVIKVPSDLDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTV
AEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVL
GRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPN
FLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLT
Ligand information
>4zq9 Chain E (length=21) [
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cgcccagcgagcgagcgagcg
Receptor-Ligand Complex Structure
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PDB
4zq9
Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
S102 M103 G106 K136 R138 G142 G143 G144 N145
Binding residue
(residue number reindexed from 1)
S97 M98 G101 K131 R133 G137 G138 G139 N140
Binding affinity
PDBbind-CN
: Kd=128nM
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
External links
PDB
RCSB:4zq9
,
PDBe:4zq9
,
PDBj:4zq9
PDBsum
4zq9
PubMed
26370092
UniProt
P03132
|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)
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