Structure of PDB 4zpr Chain B Binding Site BS02

Receptor Information
>4zpr Chain B (length=279) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTI
SYLRVRKLLDCFYLKALDGFVMVLTDDGDMVYISDNVNKYMGLTQFELTG
HSVFDFTHPCDHEEMREMLTTQRSFFLRMKCTLTRTMNIKSATWKVLHCT
GHIHCLVLICEPIPHPSNIESKTFLSRHSLDMKFSYCDITELMGYEPEEL
LGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQ
ATVIYNTKNSQPQCIVCVNYVVSGIIQHD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zpr Structural integration in hypoxia-inducible factors.
Resolution3.902 Å
Binding residue
(original residue number in PDB)
S22 R23 R27 R30 D55 K56
Binding residue
(residue number reindexed from 1)
S8 R9 R13 R16 D41 K42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4zpr, PDBe:4zpr, PDBj:4zpr
PDBsum4zpr
PubMed26245371
UniProtQ61221|HIF1A_MOUSE Hypoxia-inducible factor 1-alpha (Gene Name=Hif1a)

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