Structure of PDB 4wu8 Chain B Binding Site BS02

Receptor Information
>4wu8 Chain B (length=82) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAV
TYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>4wu8 Chain J (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagatactaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgattcagctgaacatgccttttgatggagc
agtttccaaatacacttttggtagtatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB4wu8 Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		V21 R35 R45 I46 S47 G48 R78 K79 T80
Binding residue
(residue number reindexed from 1)		V1 R15 R25 I26 S27 G28 R58 K59 T60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wu8, PDBe:4wu8, PDBj:4wu8
PDBsum4wu8
PubMed25916851
UniProtP62799|H4_XENLA Histone H4

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