Structure of PDB 4u7d Chain B Binding Site BS02

Receptor Information
>4u7d Chain B (length=527) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFLV
MPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATMLN
ASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARR
FTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVL
TDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRY
KGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSA
NEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKA
DCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQHF
DEVWACNKMCDNCCKDSAFERKNITEYCRDLIKILKQAEELNEKLTPLKL
IDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYA
TISYLKIGPKANLLNNEAHAITMQVTK
Ligand information
Receptor-Ligand Complex Structure
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PDB4u7d Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T511 L513 Y569
Binding residue
(residue number reindexed from 1)		T446 L448 Y504
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:4u7d, PDBe:4u7d, PDBj:4u7d
PDBsum4u7d
PubMed25831490
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

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