Structure of PDB 4qot Chain B Binding Site BS02

Receptor Information
>4qot Chain B (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTL
LATLKKTGKTVSYLGLE
Ligand information
Ligand IDPT
InChIInChI=1S/Pt/q+2
InChIKeyHRGDZIGMBDGFTC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Pt++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Pt+2]
FormulaPt
NamePLATINUM (II) ION
ChEMBL
DrugBank
ZINC
PDB chain4qot Chain B Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4qot Oxaliplatin Binding to Human Copper Chaperone Atox1 and Protein Dimerization
Resolution2.2 Å
Binding residue
(original residue number in PDB)		K3 C41
Binding residue
(residue number reindexed from 1)		K2 C40
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.3.54: Transferred entry: 7.2.2.8.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016530 metallochaperone activity
GO:0016531 copper chaperone activity
GO:0032767 copper-dependent protein binding
GO:0046872 metal ion binding
GO:1903136 cuprous ion binding
Biological Process
GO:0006825 copper ion transport
GO:0006878 intracellular copper ion homeostasis
GO:0006979 response to oxidative stress
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qot, PDBe:4qot, PDBj:4qot
PDBsum4qot
PubMed27305454
UniProtO00244|ATOX1_HUMAN Copper transport protein ATOX1 (Gene Name=ATOX1)

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