Structure of PDB 4qmg Chain B Binding Site BS02
Receptor Information
>4qmg Chain B (length=309) Species:
9606
(Homo sapiens) [
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PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAAT
QPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGK
DTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSH
TIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTV
MLSGIKCPTFRDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNIL
GTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLR
IWRDYVAPT
Ligand information
>4qmg Chain G (length=15) Species:
9606
(Homo sapiens) [
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PNSDWNAPAEEWGNW
Receptor-Ligand Complex Structure
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PDB
4qmg
Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
Resolution
2.701 Å
Binding residue
(original residue number in PDB)
G42 P43 R87 K88 G92 F244 E247 F250 S254 R255 L256 R259 D260 H279 N281 F293 R324 R327
Binding residue
(residue number reindexed from 1)
G26 P27 R71 K72 G76 F220 E223 F226 S230 R231 L232 R235 D236 H255 N257 F269 R300 R303
Enzymatic activity
Enzyme Commision number
3.1.31.1
: micrococcal nuclease.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0004518
nuclease activity
View graph for
Molecular Function
External links
PDB
RCSB:4qmg
,
PDBe:4qmg
,
PDBj:4qmg
PDBsum
4qmg
PubMed
25242325
UniProt
Q7KZF4
|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)
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