Structure of PDB 4qmg Chain B Binding Site BS02

Receptor Information
>4qmg Chain B (length=309) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAAT
QPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGK
DTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSH
TIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTV
MLSGIKCPTFRDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNIL
GTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLR
IWRDYVAPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
Resolution2.701 Å
Binding residue
(original residue number in PDB)
G42 P43 R87 K88 G92 F244 E247 F250 S254 R255 L256 R259 D260 H279 N281 F293 R324 R327
Binding residue
(residue number reindexed from 1)
G26 P27 R71 K72 G76 F220 E223 F226 S230 R231 L232 R235 D236 H255 N257 F269 R300 R303
Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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