Structure of PDB 4pei Chain B Binding Site BS02
Receptor Information
>4pei Chain B (length=349) Species:
5759
(Entamoeba histolytica) [
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QIQHIAIVGSVHGKYREMYRQLSEYEKSTGKEISFVICTGDMQTLRYEAD
LVYLKVPPKYKQMGDFHLYYEGKEKAPYLTLFIGGNHESSNVLLHLYNGG
FVCFNMYYLGVCSCININGLRIVGVSGIYKSFDEKKPYTYPPSPNDVVSL
FHTRNYVIQMLSNLSQSSQIDISLSHDWPQGIVMKGNYKQLYRFQPGFKK
DGASLGSPINKVILNTLKPKYWISGHMHCEYHAEEGPTHFIALGKIGYKN
AISYLDLPLKQKTDLEYDKDWVCNLIMTWPAFSNKAQFPDLSYSISELLS
KRTKELDKKIIELWEKYIGLKIIYDSDTFDIQFTSRRFYIEKIYNELNI
Ligand information
>4pei Chain R (length=1) [
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u
.
Receptor-Ligand Complex Structure
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PDB
4pei
Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
D45 N90 H91 H230 H232
Binding residue
(residue number reindexed from 1)
D41 N86 H87 H226 H228
Enzymatic activity
Enzyme Commision number
3.1.4.-
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0005506
iron ion binding
GO:0008270
zinc ion binding
GO:0008419
RNA lariat debranching enzyme activity
GO:0016787
hydrolase activity
GO:0030145
manganese ion binding
GO:0046872
metal ion binding
Biological Process
GO:0000375
RNA splicing, via transesterification reactions
GO:0000398
mRNA splicing, via spliceosome
GO:0006397
mRNA processing
Cellular Component
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0048471
perinuclear region of cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4pei
,
PDBe:4pei
,
PDBj:4pei
PDBsum
4pei
PubMed
25123664
UniProt
C4M1P9
|DBR1_ENTH1 Lariat debranching enzyme (Gene Name=DBR1)
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