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Receptor Information

>4ohf Chain B (length=458) Species: 272624 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DTHKVFVNRIINMRKIKLIGLDMDHTLIRYNSKNFESLVYDLVKERLAES
FHYPEEIKKFKFNFDDAIRGLVIDSKNGNILKLSRYGAIRLSYHGTKQIS
FSDQKKIYRSIYVDLGDPNYMAIDTSFSIAFCILYGQLVDLKDTNPDKMP
SYQAIAQDVQYCVDKVHSDGTLKNIIIKNLKKYVIREKEVVEGLKHFIRY
GKKIFILTNSEYSYSKLLLDYALSPFLDKGEHWQGLFEFVITLANKPRFF
YDNLRFLSVNPENGTMTNVHGPIVPGVYQGGNAKKFTEDLGVGGDEILYI
GDHIYGDILRLKKDCNWRTALVVEELGEEIASQIRALPIEKKIGEAMAIK
KELEQKYVDLCTRSIDESSQQYDQEIHDLQLQISTVDLQISRLLQEQNSF
YNPKWERVFRAGAEESYFAYQVDRFACIYMEKLSDLLEHSPMTYFRANRR
LLAHDIDI

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

4ohf Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4ohf Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.
Resolution	2.53 Å
Binding residue (original residue number in PDB)	D23 D25 D303
Binding residue (residue number reindexed from 1)	D22 D24 D302
Annotation score	1

Enzyme Commision number

	Molecular Function
GO:0008253	5'-nucleotidase activity
GO:0016787	hydrolase activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

PDB	RCSB:4ohf, PDBe:4ohf, PDBj:4ohf
PDBsum	4ohf
PubMed	24456211
UniProt	Q5ZZB6

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Structure of PDB 4ohf Chain B Binding Site BS02