Structure of PDB 4nyn Chain B Binding Site BS02

Receptor Information
>4nyn Chain B (length=132) Species: 64091 (Halobacterium salinarum NRC-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVHAYFDGASRGNPGPAAVGWVLVSGDGGIVAEGGDTIGRATNNQAEYD
ALIAALEAAADFGFDDIELRGDSQLVEKQLTGAWDTNDPDLRRKRVRARE
LLTGFDDWSITHVPRATNERADALANEALDDA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain4nyn Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4nyn Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
Resolution1.41 Å
Binding residue
(original residue number in PDB)		D75 D189
Binding residue
(residue number reindexed from 1)		D8 D122
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4nyn, PDBe:4nyn, PDBj:4nyn
PDBsum4nyn
PubMed
UniProtQ9HSF6|RNH_HALSA Ribonuclease HI (Gene Name=rnhA)

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