Structure of PDB 4nnu Chain B Binding Site BS02

Receptor Information
>4nnu Chain B (length=192) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4nnu Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Resolution2.81 Å
Binding residue
(original residue number in PDB)
K52 Y103 W107
Binding residue
(residue number reindexed from 1)
K9 Y60 W64
Binding affinityPDBbind-CN: Kd=7.4nM
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4nnu, PDBe:4nnu, PDBj:4nnu
PDBsum4nnu
PubMed24435062
UniProtQ00059|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)

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