Structure of PDB 4nb3 Chain B Binding Site BS02

Receptor Information
>4nb3 Chain B (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMVGQLSRGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSD
GLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILME
LEVLKSAEAVGVKIGNPVPYNE
Ligand information
Receptor-Ligand Complex Structure
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PDB4nb3 Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A.
Resolution1.35 Å
Binding residue
(original residue number in PDB)
I33 T35 R41 R43 F56 M57 T60 I83 N85 L87 K88 R91
Binding residue
(residue number reindexed from 1)
I35 T37 R43 R45 F58 M59 T62 I85 N87 L89 K90 R93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4nb3, PDBe:4nb3, PDBj:4nb3
PDBsum4nb3
PubMed24491171
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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