Structure of PDB 4lps Chain B Binding Site BS02

Receptor Information
>4lps Chain B (length=215) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKNDIKAAEMKERYLKEGLYVLNFMSSPGSGKTTMLENLADFKDFKFCVV
EGDLQTNRDADRLRKKGVSAHQITTGEACHLEASMIEGAFDLLKDEGALE
KSDFLIIENVGNLVCPSSYNLGAAMNIVLLSVPEGDDKVLKYPTMFMCAD
AVIISKADMVEVFNFRVSQVKEDMQKLKPEAPIFLMSSKDPKSLEDFKNF
LLEKKRENYQSTHSF
Ligand information
Ligand IDNI
InChIInChI=1S/Ni/q+2
InChIKeyVEQPNABPJHWNSG-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ni++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ni+2]
FormulaNi
NameNICKEL (II) ION
ChEMBL
DrugBankDB14204
ZINC
PDB chain4lps Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4lps Relationship between Ni(II) and Zn(II) Coordination and Nucleotide Binding by the Helicobacter pylori [NiFe]-Hydrogenase and Urease Maturation Factor HypB.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C106 C142
Binding residue
(residue number reindexed from 1)		C79 C115
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0016151 nickel cation binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0051604 protein maturation

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Molecular Function
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Biological Process
External links
PDB RCSB:4lps, PDBe:4lps, PDBj:4lps
PDBsum4lps
PubMed24338018
UniProtO25560|HYPB_HELPY Hydrogenase/urease maturation factor HypB (Gene Name=hypB)

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