Structure of PDB 4lnq Chain B Binding Site BS02

Receptor Information
>4lnq Chain B (length=192) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYYRVKVFNMDL
KEKFTENKFITISKYFNSSGILEINETATVSEAAPNQMFEVPKNIIRSAK
ETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDK
EQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGEKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4lnq Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		S166 H222 R224 K225 G226
Binding residue
(residue number reindexed from 1)		S113 H169 R171 K172 G173
Binding affinityPDBbind-CN: Kd=1.33uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:4lnq, PDBe:4lnq, PDBj:4lnq
PDBsum4lnq
PubMed24419611
UniProtQ9R002|IFI2_MOUSE Interferon-activable protein 202 (Gene Name=Ifi202)

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