Structure of PDB 4lhd Chain B Binding Site BS02

Receptor Information
>4lhd Chain B (length=940) Species: 1111708 (Synechocystis sp. PCC 6803 substr. Kazusa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIAVDLTKLEEKLAPADSFLDRHLGPGETEQRQMLQTLGFDTLGDLIDQA
VPPAIRFPRSLQLPASQSEYGAIAQLKSIASKNQVFRSYIGMGYYDTITP
PVIQRNILENPGWYTAYTPYQAEIAQGRLEALLNFQTMVMDLTGLEIANA
SLLDEGTAAAEAMALSYGVSKSKANAFFVAQDCHPQTIEVIKTRANPLGI
EVIVGDHHTFSFSTSIFGALLQYPATDGAVYDYRSFIDKAHQHQALVTLA
ADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAAYFATKAEYQRK
MPGRIVGVSKDAHGNPALRLALQSNICTAQVLLAVMASMYGVYHGSTGLK
NIALRIHQLTVLLAIGLKRLNYSLNNDYFFDTLRVGVGEQSAPAILKAAE
GRGINLRPLVPGEVGISLDETVTVQDLLDLWQVFAGKDNLPFTPEELWSE
VKTSFPADLTRQSLYLQDAVFNQYHSETELLRYLHQLESKDLALNTSMIP
LGSCTMKLNATAEMMPVTWPEFGKIHPFAPAGQTEGYQILFAQLEAWLGE
ITGFDAISLQPNAGSQGEYAGLQVIRQYHLSRGEEQRNICLIPESAHGTN
PASAVMCGMQVVPVKCDGEGNIDVEDLTSKAEKYGDRLAALMVTYPSTHG
VFEATIGTICDIVHRFGGEVYMDGANMNAQVGLCRPADFGADVCHLNLHK
TFCIPHGGGGPGMGPIGVKSHLQAFLPRTDQSIGMISAAPYGSASILVIS
WMYIAMMGPQGLTKATEVAILSANYMAKRLENYYPILFRGNNELVAHECI
LDLRPLKKQAAIEVEDVAKRLMDFGFHAPTVSWPVLGTMMVEPTESESLG
ELDRFCDAMIAIYQEAQAITHGEIDPADNPLKNAPHTAQSLICGEWNHPY
SQEEAAYPAPWTKQFKFWPAVGRINNTYGDRHLVCSCEGM
Ligand information
Ligand IDBCT
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)(O)[O-]
CACTVS 3.341OC([O-])=O
ACDLabs 10.04[O-]C(=O)O
FormulaC H O3
NameBICARBONATE ION
ChEMBL
DrugBank
ZINC
PDB chain4lhd Chain B Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4lhd Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation.
Resolution1.7959 Å
Binding residue
(original residue number in PDB)		F863 E888 R891 W948
Binding residue
(residue number reindexed from 1)		F826 E851 R854 W911
Annotation score1
Enzymatic activity
Enzyme Commision number 1.4.4.2: glycine dehydrogenase (aminomethyl-transferring).
Gene Ontology
Molecular Function
GO:0004375 glycine dehydrogenase (decarboxylating) activity
GO:0016491 oxidoreductase activity
GO:0016594 glycine binding
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006544 glycine metabolic process
GO:0006546 glycine catabolic process
GO:0019464 glycine decarboxylation via glycine cleavage system
Cellular Component
GO:0005829 cytosol
GO:0005960 glycine cleavage complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lhd, PDBe:4lhd, PDBj:4lhd
PDBsum4lhd
PubMed24121504
UniProtP74416|GCSP_SYNY3 Glycine dehydrogenase (decarboxylating) (Gene Name=gcvP)

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