Structure of PDB 4ld4 Chain B Binding Site BS02

Receptor Information
>4ld4 Chain B (length=182) Species: 228410 (Nitrosomonas europaea ATCC 19718) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHMNDALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVRANIAADGGPF
AAAVFERDSGLLIAAGTNRVVPGRCSAAHAEILALSLAQAKLDTHDLSAD
GLPACELVTSAEPCVMCFGAVIWSGVRSLVCAARSDDVEAIGFDEGPRPE
NWMGGLEARGITVTTGLLRDAACALLREYNAC
Ligand information
Ligand IDCYT
InChIInChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
InChIKeyOPTASPLRGRRNAP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C1N=CC=C(N)N1
OpenEye OEToolkits 1.5.0C1=C(NC(=O)N=C1)N
CACTVS 3.341NC1=CC=NC(=O)N1
FormulaC4 H5 N3 O
Name6-AMINOPYRIMIDIN-2(1H)-ONE;
CYTOSINE
ChEMBLCHEMBL15913
DrugBank
ZINCZINC000000895210
PDB chain4ld4 Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ld4 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Resolution3.0 Å
Binding residue
(original residue number in PDB)		F48 N66 H77
Binding residue
(residue number reindexed from 1)		F50 N68 H79
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.-.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047974 guanosine deaminase activity
Biological Process
GO:0006152 purine nucleoside catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4ld4, PDBe:4ld4, PDBj:4ld4
PDBsum4ld4
PubMed24083949
UniProtQ82Y41

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