Structure of PDB 4i9q Chain B Binding Site BS02

Receptor Information
>4i9q Chain B (length=873) Species: 12353 (Escherichia phage RB69) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF
DIYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYE
IKYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFD
LLNSPYGNVEEWSIEIAAKLQEQGGDEVPSEIIDKIIYMPFDNEKELLME
YLNFWQQKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRV
KVIENMYGSREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNV
GKLKYDGPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYY
AKIQIQSVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPI
PNRYKYVMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERP
SDVYSCSPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNGEIIK
EALKKLSAKSLNEMLFRAQRTEVAGMTAQINRKLLINSLAGALGNVWFRY
YDLRNATAITTFGQMALQWIERKVNEYLNEVCGTEGEAFVLYGDTDSIYV
SADKIIDKVGESKFRDTNHWVDFLDKFARERMEPAIDRGFREMCEYMNNK
QHLMFMDREAIAGPPLGSKGIGGFWTGKKRYALNVWAMEGTRYAEPKLKI
MGLETQKSSTPKAVQKALKECIRRMLQEGEESLQEYFKEFEKEFRQLNYI
SIASVSSANNIAKYDVGGFPGPKCPFHIRGILTYNRAIKGNIDAPQVVEG
EKVYVLPLREGNPFGDKCIAWPSGTEITDLIKDDVLHWMDYTVLLEKTFI
KPLEGFTSAAKLDYEKKASLFDM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4i9q A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		N284 D621 D623 M728 G729 Q733 S735 S784 N786 Y791 H804
Binding residue
(residue number reindexed from 1)		N284 D594 D596 M701 G702 Q706 S708 S757 N759 Y764 H777
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4i9q, PDBe:4i9q, PDBj:4i9q
PDBsum4i9q
PubMed24116139
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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