Structure of PDB 4gqt Chain B Binding Site BS02

Receptor Information
>4gqt Chain B (length=209) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQAL
TEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSG
TKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWES
SAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFI
GYPIKLVVE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4gqt Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4gqt N-terminal domain of C. elegans Hsp90
Resolution2.15 Å
Binding residue
(original residue number in PDB)		E30 H198
Binding residue
(residue number reindexed from 1)		E28 H196
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4gqt, PDBe:4gqt, PDBj:4gqt
PDBsum4gqt
PubMed
UniProtQ18688|HSP90_CAEEL Heat shock protein 90 (Gene Name=daf-21)

[Back to BioLiP]