Structure of PDB 4fuk Chain B Binding Site BS02

Receptor Information
>4fuk Chain B (length=328) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMKTFDFTGPLRPGKITPRRAVPSHILRPDYADRAGGVSASEEKDRGSKV
KVYNIQFLHDDSKKTAEIQRIKTVCQLSREVLDIATAAAKPGITTDELDR
IVHEATVERNMYPSPLNYYGFPKSVCTSVNEVICHGIPDSRELEEGDILN
IDVSSYLNGFHGDLNETVFIGRPDDDSVRLVHAAYECLCAGIGVVKPEAL
YKQVGDAIEACASQYQCSVVRTYTGHGVGHLFHTSPTVCHYANNKSLGMM
RPGHVFTIEPMINLGTWQDVTWPDKWTSTTKDGRRSAQFEHTMVVTNGGV
EIFTDWVDGVPTYQKQLKEWGIMLPQRK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4fuk Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4fuk Aminpeptidase from Trypanosoma brucei (CASP Target)
Resolution1.75 Å
Binding residue
(original residue number in PDB)		D211 D222 E349
Binding residue
(residue number reindexed from 1)		D152 D163 E290
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.18: methionyl aminopeptidase.
Gene Ontology
Molecular Function
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4fuk, PDBe:4fuk, PDBj:4fuk
PDBsum4fuk
PubMed
UniProtQ4FKC0

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